The current global distribution of the cactus family is being radically changed by humans, and no attempt has been made to assess the status of each species in terms of invasion or risk thereof. Consequently, a broad global assessment of the determinants of invasiveness of the family Cactaceae is an important requirement for the formulation of control strategies. Moreover, reviewing the invasive performance of this family around the world may uncover new patterns, processes and invasion risks not seen in better-studied model groups.