Although it remains the reference standard treatment of muscleinvasive
and high-risk urothelial bladder carcinoma, radical cystectomy
(RC) is associated with significant risks of perioperative and
long-term morbidity and mortality, notably due to renal function
impairement.2,3 Despite the variety of diversion techniques, either
continent or noncontinent, patients undergoing RC have a life-long
risk of CKD. Several factors have been identified to explain the
renal function decrease, including nonmodifiable parameters such as
age, the nephrotoxicity of chemotherapy or medical treatment,
chronic hypertension, and diabetes mellitus, and potentially modi-
fiable factors, including mechanical obstruction and urinary tract
infection