Given the low capacity of SC-CO2 to extract antioxidant compounds
from mango leaves, the addition of co-solvents was
necessary to improve the quality of extracts. The solubility of
polar substances, such as polyphenols, in SC-CO2 is very low
[10–14,38–40], however the use of organic co-solvents increases
the solvent power of CO2 and the extraction yield [7,18,38–40]