Among the lipid metabolic disorders, one of the
hypotheses of why the injury of atherosclerosis occurs
proposes that the first step of the atherogenesis is the
induced endothelial dysfunction, especially through
the vascular edothelium exposure to the oxidized
low-density lipoprotein (LDL-ox). The high-density
lipoproteins (HDL) play a protective role against
the development of atherosclerosis, inhibiting the
oxidation of LDL (Assmann and Nofer, 2003).