Negative effects[edit]
Caffeine can increase blood pressure in non-habitual consumers.[8] High blood pressure is associated with an increase in strokes, and cerebral vascular disease, which in turn increase the risk of multi-infarct dementia.[8]
Caffeine may reduce control of fine motor movements (e.g. producing shaky hands)[4]
Caffeine can increase cortisol secretion, some tolerance is developed.[9]
Caffeine can contribute to increased insomnia and sleep latency.[4]
Dependence can occur with caffeine.[4][10]
High caffeine consumption may accelerate bone loss in postmenopausal women.[10][11]
Caffeine does not improve memory and cognitive function, unlike Acetylcholine, which is associated with increased attention, concentration, learning, and memory.