2.1. Materials
Poly-ε-caprolactone (PCL; Mw 45,000; Sigma Aldrich), absolute
ethanol (Penta Chemicals) and chloroform (Penta Chemicals) were
used for the composite materials production.
2.2. Scaffold fabrication
Solution of 16 wt% polycaprolactone (PCL) in chloroform/ethanol
(9:1) was prepared for the electrospinning process. The
scheme of the production equipment set-up in optimal conditions
is shown in Fig.1. The set-up was composed of a meltblown device
(J&M Laboratories), an electrospinning device (a multi needle
spinner and a countervailing pressure cylinder) and computercontrolled
pumps. The meltblown extruder screw rotated at 3–
15 rpm for 30–120 min, respectively (depending on the ratio of
micro- and nanofibers in the sample). 100 g of polymer per sample
was always extruded. Air velocity was 20 ms1 at 200 mm from a