The insertion of heme iron into TPO is necessary for the enzyme to translocate to the apical cell surface of thyrocytes (or thyroid epithelial cells), thus assisting TPO to catalyze the two initial steps of thyroid hormone synthesis
The insertion of hemeiron into TPO is necessary for the enzyme to translocate tothe apical cell surface of thyrocytes (or thyroid epithelialcells), thus assisting TPO to catalyze the two initial steps ofthyroid hormone synthesis