presumed infections in febrile neutropenic patients, septicemia 1 g 8 hrly. Meningitis 2 g 8 hrly. Renal impairment Adjust dosage based on CrCl. Childn >50 kg Usual adult dose. Childn 3 mth-12 yr 10-20 mg/kg 8 hrly. Meningitis 40 mg/kg 8 hrly. Febrile neutropenic patients 20 mg/kg 8 hrly.