The insulin-like growth factor 2 (IGF2) involved in cell
proliferation, differentiation, apoptosis and transformation,
has high expression in liver, intestine and adrenal glands at
embryo stage, and is suppressed after birth. It can stimulate
the proliferation and differentiation of muscle fibers with
concentration-dependent manner. The causative mutation
g.3072G[A has been identified in a highly conserved
regulatory region of intron 3 of IGF2 gene with substantial
effect on muscle growth and backfat thickness [1]. Several
studies indicate that the porcine IGF2 gene have an impact
on growth rate, intramuscular fat content, percentage of
lean, backfat thickness, loin eye area, and carcass weight of
pigs [2–7].