The developing and under developed countries mostly rely on traditional medicines. This
herbal or traditional medicine involves the use of different types of organic extracts or the bioactive
chemical constituents. This type of biochemical investigation provides health care at an affordable
cost. This survey such as ethnomedicine keenly represents one of the best avenues in searching new
economic plants for medicines. Keeping this view in mind, the present study is carried out in Merremia
borneensis leaves of University Malaysia Sabah, Sabah, Malaysia. The plant has several beneficial
properties, such as antioxidant activity. The dry powder of the leaves of M. borneensis was
extracted with hexane, ethyl acetate, chloroform, butanol and aqueous ethanol. The flavonoids content
of the extracts was determined by Willet method. The flavonoids content of the extracts as
quercetin equivalents was found to be highest in aqueous ethanol (53.28%) followed by chloroform
(38.83%), ethyl acetate (24.51%), butanol (12.54%) and hexane extract (3.44%). The results suggest
the presence of phytochemical properties in the leaves, which are used in curing the ailments