By 1900 the German chemical industry dominated the world market for synthetic dyes. The three major firms BASF, Bayer and Hoechst produced several hundred different dyes, along with the five smaller firms. In 1913 these eight firms produced almost 90 percent of the world supply of dyestuffs, and sold about 80 percent of their production abroad. The three major firms had also integrated upstream into the production of essential raw materials and they began to expand into other areas of chemistry such as pharmaceuticals, photographic film, agricultural chemicals and electrochemical. Top-level decision-making was in the hands of professional salaried managers, leading Chandler to call the German dye companies "the world's first truly managerial industrial enterprises".[103] There were many spin offs from research—such as the pharmaceutical industry, which emerged from chemical research