As thermoplastic synthetic polymers with desirable
mechanical propertyprofile, biocompatibility andbiodegrad-ability, polylactic acid (PLA) and polyurethane (PU) are two
of the most promising biopolymers for tissue engineering
territory, such as bone scaffolds, vascular grafts, and heart
valves [14, 15]. Moreover, PU exhibits a certain degree of
antibacterial efficacy [16, 17]. Compared with scaffolds fabri-cated fromPLA or PU alone [18], it has been known that the
composite PLA/PU scaffold exhibits advantageous morphol-ogy, mechanics, cell adhesion, and growth-supporting prop-erties. However, dissatisfactory antibacterial activity coming
from PU phase in PLA/PU composite limits its practical
application in tissue engineering fields.