The microemulsions loaded with curcumin were also characterized
by DLS, to highlight if the presence of this molecule in oil
droplets may affect on size, polidispersity and stability. In fact,
some drugs tend to localize more to the interface and this depends
on both their chemical structure and the presence of surfactants/
co-surfactants at the interface. This would lead to a greater solubility
of the substance in the system, but at the same time, could
destabilize the microemulsions. The localization of the compound
at the interface may partially move the surfactants/cosurfactants
from the interface making the system less stable, thereby
increasing the size of the dispersed phase.