Free radical generation through biological oxidation process in cellular system leads to
liberation of energy by conversion of large molecules to small molecules and more precisely
to complex metabolites to their simple forms. These free radicals are known as pro oxidants
and the molecule that regulates the generation of free radicals are called antioxidants.
[1] An
imbalance between pro oxidant and antioxidant level in cell leads to excessive generation of
radical species and thus causes high degree of biomolecule damage and hence eventually
damage the cellular components.
[2] Nucleic acids (DNA and RNA) are one of the very