Lack of saliva increases the risk of developing caries (particularly at the cervical
and root areas of the teeth), enamel erosions and periodontal diseases [1,2,33].
Study of Yeh et al. [57] provided the evidence that hyperglycemia in combination
with reduced saliva in a model of type1 DM leads to decreased enamel mineralization/
matrix proteins and predisposes to excessive wearing and decay. Importantly,
hyperglycemia adversely affects enamel matrix proteins and pulp repair. Early detection
and treatment of hyperglycemia and hyposalivation may provide a usefulstrategy for preventing the dental complications of diabetes and promoting oral health
in this population.