The online diabetes self-management system was developed using C# programming language and a Microsoft SQL server. It was integrated with an off-the-shelf 3G glucometer [14]. The infrastructure design of the online diabetes self-management system is shown in Figure 1. According to the scheme mentioned above, each patient is assigned a unique identification and password, which allows them to log in, edit, and manage their information. The online diabetes self-management system is a Web-based system accessible on the Internet and not limited to operating systems or devices. It adopted the continuity of care document (CCD) standard to enhance the interoperability of data. The 3G glucometer facilitated easy and automatic data uploading after each measurement anywhere and combined blood pressure, blood glucose, and heart rate measurements in 1 instrument.