The thalassemia are classified according to the hemoglobin chain affected and the amount of the globin chain that is synthesized. The two major categories are α-thalassemia and β – thalassemia. Thaslasemia is seen in vatious population group, such as Asians, African-American, Italians, and inhabitanes of the Middle F astern regions, and the majority of births of affected individuals occur in these groups