All animals developed an acute lethal course of ASF with high fever (see Fig. 2), depression, reduced feedintake, slight central nervous signs, and conjunctivitis. Some animals showed in addition gastro-intestinal and respiratory signs. Allanimals succumbed to infection within 12 days and showed path-omorphological lesions indicative for ASF including enlarged andhaemorrhagic gastro-hepatic lymphnodes and lung oedema. Virusand genome detection was comparable among animals with strongpositive reactions from 5 dpc (data not shown). Following chal-lenge infection, antibodies dropped in several immunized animalsindicating consumption. These reactions were most pronounced ingroup T01 at 5 dpc. In this group only one animal remained doubt-ful at 5 dpc (see Fig. 1). All but one of the vaccinated animals waspositive by the day of euthanasia. No antibodies could be detectedin the controls (see Fig. 1).