Keep questions to a very few.
It can be gruelling to be up-front and handling questions. I would recommend five or six at most, and when you’ve reached five, make it clear you’re about to end: “I’ll take this question and one more, then we’ll wrap it up.”
If they clearly still have more to ask, advise them to send by email or to approach you afterwards. Being accessible is important: it makes clear that you genuinely want the audience to take action on your message.