This white paper focuses on the analysis of excipient materials doped with known concentrations of metals. Standard samples were produced using fine excipient grade cellulose and pure organo-metallic compounds. ICP-MS techniques were employed to independently confirm the concentrations of elements in each standard. These standards were prepared and measured as both loose powders and pressed pellets. All loose powder standards and samples were weighed into disposable sample cups with 4.2 micrometer polypropylene support film. Compton ratio corrections were employed to account for any minor variations in sample packing. All pressed pellets were produced without a binder and pressed for 60 seconds at 10 tons.