OLVING POWER, DYNAMIC RANGE, AND HIGH SENSITIVITY
The hybrid FT mass spectrometer combines a linear ion trap
MS and the Orbitrap mass analyzer. Ions generated by API
are collected in the LTQ XL followed by axial ejection to the
C-shaped storage trap which is used to store and collisionally
cool ions before injection into the orbital trap. The ions
transferred from the C-Trap are captured in the orbital trap
by rapidly increasing the electric field and the detection of
the image current from coherent ion packets takes place
after the voltages have stabilized. Signals from each of the
orbital trap outer electrodes are amplified and transformed
into a frequency spectrum by fast Fourier transformation
which is finally converted into a mass spectrum.
Additionally, the LTQ Orbitrap XL features a new
collision cell to provide additional flexibility to any MS/MS
experiment. Ions can be selected in the linear ion trap and
fragmented either in the ion trap (CID) or in the new collision
cell (HCD). For HCD (Higher Energy Collisional Dissociation)
ions are passed through the C-trap into the gas-filled
collision cell. Normalized Collision Energy in HCD MS/MS
experiments provides reproducible data from instrument
to instrument.
LTQ ORBITRAP XL –
UNRIVALED PERFORMANCE AND FLEXIBILITY
• Features the new HCD (Higher Energy Collisional Dissociation)
collision cell for ultimate flexibility in fragmentation experiments
for advanced proteomics and small molecule research
• Future upgrades will include ETD (Electron Transfer Dissociation)
and MALDI capabilities
Based on the fast and highly sensitive Thermo Scientific LTQ XL™ linear ion trap
and the patented Orbitrap™ technology, the LTQ Orbitrap XL hybrid FTMS
(Fourier Transform Mass Spectrometer) supports a wide
range of applications from routine compound
identification to the most challenging analysis
of low level components in complex mixtures.