In conclusion, b-thalassemia intermedia during pregnancy can present unique management challenges and requires close maternal and fetal surveillance. Management of those patients should be individualized until more clinical trials evaluate the role of routine blood
transfusions, preconceptional chelation, splenectomy,and thromboprophylaxis requirements in such patients that might impact their obstetric outcome. Care for such pregnancies should be multidisciplinary, incorporating a maternal-fetal medicine specialist, a genetic
counselor, and a hematologist. Although our patients did not experience cardiac, hemodynamic, hepatic, or kidney deterioration during pregnancy, other complications
can occur, which stresses the need for careful monitoring throughout pregnancy.
In conclusion, b-thalassemia intermedia during pregnancy can present unique management challenges and requires close maternal and fetal surveillance. Management of those patients should be individualized until more clinical trials evaluate the role of routine bloodtransfusions, preconceptional chelation, splenectomy,and thromboprophylaxis requirements in such patients that might impact their obstetric outcome. Care for such pregnancies should be multidisciplinary, incorporating a maternal-fetal medicine specialist, a geneticcounselor, and a hematologist. Although our patients did not experience cardiac, hemodynamic, hepatic, or kidney deterioration during pregnancy, other complicationscan occur, which stresses the need for careful monitoring throughout pregnancy.
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