Similar observations were documented by Yadav and Trivedi [51] in C. punctata following exposer to sublethal concentration of chromium (VI) up to 168 h. In another study, De Lemos et al.[58] accounted significant induction of micronucleus in fish erythrocytes exposed to chromium (VI) for 21 days but with a decrease thereafter. Brunetti et al.[59] reported that the higher concentration of toxicant might inhibit normal cell division, damage chromosome and interdict DNA duplication, thus cytotoxic damage more or less declined.