Ambulatory hypertension: Ambulatory hypertension is most commonly diagnosed by a mean SBP or DBP exceeding normal values for the full 24-hour period. Other definitions include blood pressure values that exceed normal during the waking period (diurnal hypertension) or the sleep period (nocturnal or sleep hypertension). Blood pressure load has a strong predictive value for end-organ damage. Other promising analytic techniques need further validation, such as the cosinor analysis, modified LMS of Cole and Green (where the distribution of a measurement Y is described by its median [M], the coefficient of variation [S], and a measure of skewness [L] required to transform the data to normality),150 blood pressure index, and hyperbaric index.