Primary hepatocytes express PEMT but the activity starts to decline upon plating of the cells and ~50% of enzyme activity is lost after 24 h. Moreover, no suitable hepatoma cell line has been identified that has significant expression of PEMT.
Primary hepatocytes express PEMT but the activity starts to declineupon plating of the cells and ~50% of enzyme activity is lost after24 h. Moreover, no suitable hepatoma cell line has been identifiedthat has significant expression of PEMT.