Oxy but in may decrease enures u through its antimuscarinic properties and relaxant effect on urinary smooth muscle (Waterfield, 2009). This anti cholinergic medication can le used tor children with nighttime and daytime c enuresis or for those who do not re spond to desmopressin. Some evidence shows that adding oxybutin to desmo- pressin may improve results. Common side effects include dry mouth, blurred vision, headache, nausea, dizziness. gastrointestinal upset, and tachycardia (Ramakrishnan, 2008). Other medica red with tions show effectiveness compar placebo but are not more effective than (Glazener Imipramine or desmopressin et al, 2004b)