The existing variation in resistance to chlorantraniliprole may be
brought about by the genetic diversity of the test populations, different
insecticide exposure histories or other factors. To analyse the relationship
between chlorantraniliprole resistance and insecticide exposure
history, the pair-wise correlation between LC50 values of chlorantraniliprole
and the other seven insecticides were analyzed. Significant
correlation were found between chlorantraniliprole resistance and
the resistance to the abamectin, spinosad, chlorfenapyr and beta-cypermethrin
(R2 > 0.6), indicating that the resistance to chlorantraniliprole
in DBM populations was related to the resistance of these same
populations to other insecticides. The significant correlation between
the resistance to different insecticides implies that the mechanisms
of the insecticide are likely to share some common biochemical pathways
and genetic mutations resulting in resistance for one insecticide
(abamectin, spinosad, chlorfenapyr or beta-cypermethrin) was highly
likely to increase the resistance against chlorantraniliprole as well. The
correlation structure among insecticides would be great value in agriculture
applications by facilitating the design of effective insecticides
combinations and strategies