verall median survival age for adults with diabetes was 10.5 years shorter than that for matched controls without diabetes. Estimated life-years lost associated with diabetes decreased with increasing age at diagnosis from 20.0 years for those diagnosed before age 20 years to no difference for those diagnosed after 80 years. Hazard ratios for mortality decreased from 3.03 (95% CI: 2.41, 3.80) for those with diabetes diagnosed before 20 years to 1.04 (95% CI: 0.78, 1.39) for those diagnosed after 80 years. The estimate of life-years lost associated with diabetes was much higher among those with pre-existing cardiovascular disease (20.3 years) than among those without cardiovascular disease (8.5 years).