He later developed these perspectives in further publications in
which he explained how actively expressed genes could
be amplified in the genome by such a process. There fore, there could be a return from the activation state of the genome to its structure, a Lamarckian process at
the cellular level! Although the numerous `selfish ' DNA sequences in the genome of eukaryotes are probably the result of the action of reverse transcriptase, the `heretical'
propositions of Temin have not been confirmed .