In the current study, we provide evidence that malaria associated renal injury could be protected against by using
the aqueous crude extract of neem leaves in PbANKA infected mouse model. Impairment of renal function during
malaria infection has been reported by clinical reports, and it is an important life-threatening complication of malaria
infection that goes beyond the classical clinical symptoms of malaria [22, 23]. Moreover, the adversities to access of
medical services or delay in diagnosis in their place of origin is implicated in the severity of disease. The onset of renal
injury in PbANKA infected mice came out from day 4 after infection and the incidence of renal injury was confirmed
through manifestation including marked increases of plasma BUN and creatinine levels