These results have confirmed LSO
as having mainly a gram positive antibacterial spectrum, inaddition
to a limited action against gram negative bacteria. However, to our
knowledge, only two clinical trials testing the effectiveness of LSO
formulations have been reported in the literature and none have
tested LSO in a gel formulation. In addition, this study is the first to
provide clinical data on the efficacy of LSO in reducing salivary MS
in children with dental caries.