(7). It has been suggested that the reduced
amount of negatively charged peptidoglycans makes Gram-negative
bacteria such as Pseudomonas aeruginosa
and Proteus sp. less susceptible to such
positively charged antimicrobials. Studies
have been conducted to assess the potential
of nano CuO embedded in a range of
polymer materials. A lower contact-killing
ability was observed in comparison with
release killing ability against MRSA
strains. This suggests that a release of ions
into the local environment is required for
optimal antimicrobial activity