PROBABILISTIC ANALYSIS
Almost all probabilistic sensitivity analyses (>98% of simulation results) predicted cost savings for treatment of patients with stage 2 hypertension, except for women in the age group of 35 to 44 years (Fig. S3 in the Supplementary Appendix). More than 98% of probabilistic simulations were cost-effective for patients with stage 1 hypertension who were 45 years of age or older, whether male or female. About 66% of simulations for men between the ages of 35 and 44 years who had stage 1 hypertension without diabetes or chronic kidney disease and 92% of simulations for women between the ages of 35 and 44 years who had stage 2 hypertension were cost-effective, but almost none were cost-saving. None of the results for women with stage 1 hypertension between the ages of 35 and 44 years were cost-effective.