If the fetus is alive, an external monitor is placed and evidence of fetal distress is sought. If the diagnosis of abruptio placentae is clinically favored over that of placenta previa, it is highly desirable to perform ultrasonographic examination in the labor and delivery suite. A large-bore intravenous line is placed, and through it the initial blood samples for initial hemoglobin and hematocrit, blood for type-screen and cross-match, baseline electrolyte and renal function studies are useful for later comparison when massive transfusion is required as well as for later detection of renal complications. Clinically significant coagulopathy is encountered in only about 10% of cases of abruption, but it is much more common in severe abruption marked by death of the fetus or massive hemorrhage. Proper management of this disorder demands an understanding of its pathophysiology as well as correct interpretation of various laboratory tests of hemostasis and blood coagulation.