FeOx-pillared clays (FeOx-pillared bentonite, FeOx-pillared hectorite and FeOx-pillared taeniolite) were synthesized by the intercalation of FeCl3 into clay interlayers and calcination. The synthesized catalysts were exploited for conversion of epoxides furnishing acetonides in good to quantitative yields with short time under mild conditions. The catalysts could be recovered and reused up to five times without appreciable loss of activity.