Introduction
Peptic ulcer bleeding (PUB) is the most common cause
of acute hemorrhage in the upper gastrointestinal (GI)
tract. It affects 48–160 people per 100,000 adults
every year.1–3 Significant blood loss resulting from
impaired blood clotting in the acidic environment of
the GI tract may cause death in up to 14% of patients
with an acute bleed, with the risk of death increasing
3-fold in patients experiencing rebleeding