On the contrary if you were to consume 1000 calories from broccoli – a high fiber option that barely registers an effect on your blood glucose, you don’t trigger the same biochemical reaction at all. Firstly, you wouldn’t even be able to consume 1000 calories from broccoli as that would be close to 21 cups – lepton would kick in and let you know you’ve had enough and you would experience the feeling of being full. And incredibly nourished (I just love broccoli!)