Heat shock protein 90 (Hsp90) is a molecular chaperone which regulates maturation and stabilization of its substrate proteins, known as client proteins. Many client proteins of Hsp90 are involved in tumor progression and survival and therefore heat shock protein 90 (Hsp90), is one of the fundamental factors
involved in the cell response to stresses, and its role in many biochemical pathways has been
demonstrated. Thus, the inhibition of Hsp90 represents a new target of antitumor therapy.