(2) The Expression of COX-1, COX-2, and iNOS.
Figure 5 showed the expression of COX-1, COX-2, and iNOS on SCC protective effect on indomethacin-induced gastric ulcer.
The expressing of COX-1 was reduced after 20 mg/kgBW indomethacin administration and COX-2 was increased in the same group.
The iNOS protein levels in indomethacin treated mice indicated upregulated iNOS gene expression.
However, treatment with SCC significantly reduced the expression of this enzyme (