Know your significant chemical and chemical process hazards, and their related
risks for your business. This includes clearly understanding why some of the
chemicals you are handling may be dangerous - explosive, flammable, toxic,
corrosive - or harmful in some other way to humans, animals or the
environment. The hazards intrinsic to the process (e.g. pressure, temperature,
explosive dust atmospheres, electrostatic discharge) should also be known and
understood. Do not forget that some chemicals may be in ostensibly 'closed'
systems, e.g. ammonia refrigeration, hydraulic oils.