Corticosteroid and catecholamine hormones are released in response to stressors in an attempt to adapt or avoid the cause of stress. Although both types of stress hormones are released into the bloodstream as part of the integrated stress response to acute and chronic stressors they do play different roles. Catecholamines or CA is the primary hormone released in the "Fight or Flight" response to acute stressors. Corticosteriods, predominately cortisol, are the primary hormone released in response to chronic stressors.