Extracellular LiP, MnP and Laccase activities by C. globosum IMA1 C. globosum was able to grow on ITE, characterized by a COD of 2.3 g/L and equivalent indigo concentration of 0.35 g/L. It produced LiP, MnP and Laccase with high activities in both static and stirred cultures (Fig. 5). The LiP, MnP and Laccase activities were significantly favored by agitation with maximum values of 832 U/L (Fig. 5a), 250 U/L (Fig. 5b) and 83.4 U/L. Agitation increased the oxygen and nutrient transfer rate which was decisive for biomass growth and enzymes production and activities. Therefore, the high ITE decolourization was corroborated with the extracellular peroxidases and mycelium growth, which favor the biodegradation of complex molecules.