Hepatotoxins in Nature and Feed
Pyrrolizidine Alkaloids
This is a common cause of liver disease in certain regions, especially in the southeastern United States
(like Georgia). It is caused by a variety of toxic plants which contain pyrrolizidine alkaloids that cause
hepatic necrosis and fibrosis with bile duct hyperplasia.
Plants that contain pyrrolizidine alkaloids include: Amsinckia spp. (e.g. fiddleneck), Crotalaria spp. (e.g.,
Rattlebox), Cynoglossum spp. (e.g., hound’s tongue), Echium spp. (e.g., Salvation Jane), Heliotropium
spp. (e.g., common heliotrope), and Senecio spp. (e.g., ragwort, groundsel, and tar weed). Obviously this
is a problem for grazing animals only.
Hepatotoxins in Nature and Feed Pyrrolizidine AlkaloidsThis is a common cause of liver disease in certain regions, especially in the southeastern United States(like Georgia). It is caused by a variety of toxic plants which contain pyrrolizidine alkaloids that causehepatic necrosis and fibrosis with bile duct hyperplasia.Plants that contain pyrrolizidine alkaloids include: Amsinckia spp. (e.g. fiddleneck), Crotalaria spp. (e.g.,Rattlebox), Cynoglossum spp. (e.g., hound’s tongue), Echium spp. (e.g., Salvation Jane), Heliotropiumspp. (e.g., common heliotrope), and Senecio spp. (e.g., ragwort, groundsel, and tar weed). Obviously thisis a problem for grazing animals only.
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