Hair graying is one of the natural aging
processes.1 Although it is generally not a
medical problem, it greatly concerns many
people for aesthetic reasons.2 Premature hair graying
(PHG) is especially important as a cause of low
self-esteem, often impeding social life in young
people.3 Moreover, because of the strong association
between aging and hair graying, many researchers
have been concerned that PHG is a predictor of some
severe systemic disease. Several studies evaluated
the association of PHG with osteopenia or coronary
artery disease.4-6 However, the common factors