Background. This article presents evidence-based clinical recommendations for
use of pit-and-fissure sealants developed by an expert panel convened by the
American Dental Association Council on Scientific Affairs. The panel addressed the
following clinical questions: Under what circumstances should sealants be placed to
prevent caries? Does placing sealants over early (noncavitated) lesions prevent pro-
gression of the lesion? Are there conditions that favor the placement of resin-based
versus. glass ionomer cement sealants in terms of retention or caries prevention?
Are there any techniques that could improve sealants’ retention and effectiveness
in caries prevention?