The use of herbicides in production systems have allowed growers to effectively and economically control weeds. Hard to control weeds, such as field bindweed and annual morningglory, can now be effectively managed in cropping systems. Selective herbicides have allowed the reduction, and in some cases, the elimination of hand weeding all together. Cultivation has been reduced in field and vegetable crops with some movement toward reduced or minimum tillage systems. The new generation of herbicides are much more environmentally friendly, controlling weeds with only ounces of active ingredients per acre as opposed to pounds per acre required by some of the older herbicides. The introduction of herbicide tolerant crops has provided growers with an additional option for effective control. But, for herbicides to remain effective and to sustain their use, attention and consideration must be given to Herbicide Resistance.