Are the properties of 2D materials so unique to overshadow the unavoidable inconveniences of switching to a new technology? The advancing R&D activity on 2D materials has already shown a phenomenal development aimed at making 2D materials suitable for industrial applications. The production of 2D materials is one striking example of the rapid development towards commercialization, with progress from random generation of micro to large-scale flakes in the laboratory [80], roll-to roll processing of nanosheets of a size approaching the meter-scale [104].