It was latter found that the catecholamine dopamine (DA) is the single most active inhibitor of basal and GnRH-stimulated LH release.This led to the development of the "Linpe" method, named after the inventors H.R. Lin and R.E. Peter. Later, a
fish spawning induction kit called "Ovaprim™" was produced and marketed by Syndel, Inc. in Vancouver, Canada.
This method is based on the principle that blocking DA receptors in the brain and pituitary and stimulating
GnRH receptors leads to a super-stimulation of LH, mimicking the LH surge to cause ovulation or sperm release in
many but not all teleost fish