In 2009
We entered into Medical Device business with the highest technology business; especially in alternative Cancer Therapy Treatment System by High Intensity Focused Ultrasound (HIFU) and Sole Distributor of HIFU YDME AESKULAP Medical Device in South East Asia Region.
High-Intensity Focused Ultrasound (HIFU YDME AESKULAP) is a highly precise medical procedure that applies high-intensity focused sonic energy to locally heat and destroy disease or damaged Tumor Cancer tissue through ablation. Clinical HIFU YDME AESKULAP procedures are typically performed in conjunction with an imaging procedure to enable treatment planning and targeting before applying a therapeutic or ablative levels of ultrasound energy.
Currently, HIFU YDME AESKULAP has been approved therapeutic procedure to cancer treatment in various countries in Thailand, Australia, Canada, Europe, and the United States. At this time HIFU devices are cleared to be on the market in the US, Canada, EU, Australia, and several countries in Asia.
Aeskulap Clinic (Asia) is the first company to introduce HIFU therapy system in Thailand through the cooperation with Medical School of Srinakharintarawirot University (MEDSWU) to start clinical trials to evaluate the effectiveness of the HIFU YDME AESKULAP devices to ensure absolute safety and less complication for providing to the public. Now, HIFU YDME AESKULAP in operation and service at The Royal Highness Princess Maha Chakri Sirindhorn Hospitals.
In 2010
Tissue Engineering Development by Robot Automate Cell Culturing System (RCPX) with Kawasaki Heavy Industries Limited
RCPX (Robot Automated Cell Culturing Systems).
The Company has been entered to RCPX (Robot Automated Cell Culturing Systems) for regenerative medicine and cell therapy using automatic cell processing system and also invented to increase abilities in culturing cell both in term of quantity and quality. The RCPX is the robotic system in nature, it still needs competent personnel to initiate the cell line and introduce to the robotic system. Indeed, it has high efficiency to produce products in commercial scale.
RCPX (The Advantage from RCPX “Robot Automated Cell Culturing Systems”)
The Substitute of CPC (Cell Processing Center)
The automatic cell processing system will end the need of CPC with high cost of building and maintenance. As it has globe box function, it is used as an isolator. The best formation by combining of automation and manual method is achieved.
Mass production of cells in safety, steadily and stably is achieved. The individual recognition is installed on the equipments such as culture vessels, and the mix-up is prevented.
The Contamination Control by VHP (Vaporized Hydrogen Peroxide) makes sure the prevention of cross contamination between plural donors. As wastes are taken out after decontamination medical staffs are kept safety.
As commonly used culture protocols for adherent cells are automated, it enables the culture of large variety of cells with changing parameters and making software.
As all facilities are computer-controlled, all operation of the system, robot movements and the state of cell including their image data are recorded. Remote monitoring and remote control are possible using network connection.
Wide varieties of protocols for cell culture and tissue engineering are automated, example: Culture of bone marrow mesechymal stem cell, Isolating Keratinocytes Cultured Epidermis Sheet, Transplantation of Autologous Cultured Cartilage “Knee-Joint”), Transplatation of Autologous Cultured Cornea Epithelium.
The advances in the fields of biotechnology and biomaterials offer the physician the exciting possibility of repair or regeneration of tissue lost to injury, disease, or aging. The tissue-engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physic-chemical factors. The promising area of tissue engineering represents a multidisciplinary approach aimed at solving some of the most perplexing biologic problems, namely, the creation of new tissues and organs similar to the original tissues and organs. In addition, strategies using new synthetic polymer formulations can facilitate tissue replacement and represent alternatives to tissue regeneration in certain conditions.
•Cultured Epidermis is the world’s most widely used Tissue-Engineered Medical Product (TEMP). AESKULAP is the first will offer it in Thailand.Cultured Epidermis is skin cover the human body completely. An average adult
Has a total surface are of around 1.6 m2 of skin, which if subcutaneous tissue is included weight around 9 kg. Skin is the largest organ of the human body. If a burn or other trauma results in skin loss over a wide area, this seriously impairs its vital functions of maintaining body temperature and conserving fluid, and infection by bacteria that invade the body from outside also increases the risk of death. Histological, skin comprises three layers; from the outside in, these are epidermis, dermis, and subcutaneous tissue. The keratinocytes that compose the epidermis possess an extremely high ability to proliferate, meaning that skin regenerates very rapidly. When the skin is lost over a wide area, however, regeneration takes too long. A cultured epidermis had been developed that can be grafted onto the injured area, made by isolating keratinocytes from a skin biopsy, culturing them in flaks, and forming them into a skin-like sheet.
•Regenerating your own Cartilage means being able to move yours Joints just as smoothly as you used to. AESKULAP is the first will offer it in Thailand
Cultured cartilage is the thin layer that covers the bones in joints such as knees and elbows, allowing them to move smoothly over each other. In healthy adults this layer is around 2-3 mm thick, but it becomes thinner with advancing age. As cartilage tissue does not naturally recover once damaged. It is extremely difficult to treat with drugs or other therapies. Now, however the latest tissue-engineering technology means cartilage can be regenerated in a culture dish as cultured cartilage.
•Cultured Corneal Epithelium Offers a New Vision for formerly untreatable Eye Disorders. AESKULAP is the first will offer it in Thailand
Cultured cornea epithelium forms the outermost layer of the cornea in the eye. Within the cornea epithelium, Stem cells are found in the region called the limbus on the border between the cornea and the conjunctiva. In cases of severe injury to the cornea, as long as even a small patch of healthy limbus remains, cornea epithelial stem cells can be isolated from this limbus tissue and cultured to produce autologous cultured cornea epithelium. Transplanting this tissue makes it possible for patients to recover their vision unheard of with conventional treatments.
In 2012
The Company entered to an agreement with Japan Tissue Engineering Co., Ltd to penetrate the Tissue Engineering to be Regenerative Medicine for Cultured Epidermis, Transplantation of Autologous Cultured Cartilage (Knee-Joint), Cultured Corneal Epithelium
In 2013, 1st Half
The Company decided to invest into an Advance Innovation Biotechnology by building up the new building for Holistic & Wellness (Preventive and Rehabilitation), Dermatology and the highest quality of cosmetic products Centre at Centre of Bangkok City (Ngamwongwan Road) and UNESCO World Heritage at Khao Yai for 40 rai “Castle Holistic & Wellness (Preventive and Rehabilitation), Dermatology and the highest quality of Cosmetic products in the “Castle Hotel”, Total amount of investment approx. Million U.S Dollars 36.00.
In 2013, 2nd Half
The Company decided to enter into Activated Autologous Lymphocyte Therapy with Toyo Seikan Kaisha, Ltd. And Lymphotec, Inc which these new venture therapy systems will be supported and value added treatment with the existing Cancer Centre treatment by High Intensity Focused Ultrasound (HIFU YDME AESKULAP) at The Royal Highness Princess Maha Chakri Sirindhorn Hospitals.
Recents Business Developments
Thanawin Holdings Co., Ltd. was established in 1993 by Dhanakiccapavaraphan Family with the registered capital of 3.5 Million U.S. Dollars and approximately 88 Million U.S. Dollars in tangible assets.
Thanawin Holding Company is an investment company engaged in various business areas including the areas of biotechnology, import and export of biotechnology transfer, real estate development, energy supply (NGV) service provider, highest technology of medical device (HIFU YDME AESKULAP, RTM, Ozone Therapy Systems, Cycroterm, Multiwave Osilator, Acu Vision, Acu Point, Frequency Generator, etc.), dermatology and the highest quality cosmetic which they are the latest technology of skin care products as well as organic and macrobiotic serving at our quick service restaurant.
Thanawin Holding Company is also involved with the Tumor Cancer Center at The Royal Highness Princess Maha Chakri Sirindhorn, Srinakharinwirot University Hospital tissue engineering at Chulalongkorn Faculty of Medicine, immunology research at Chulalongkorn Faculty of Medicine and Chiang Mai Faculty of Medicine, Srinakarinwirot Faculty of Medicine and a wellness
In 2009
We entered into Medical Device business with the highest technology business; especially in alternative Cancer Therapy Treatment System by High Intensity Focused Ultrasound (HIFU) and Sole Distributor of HIFU YDME AESKULAP Medical Device in South East Asia Region.
High-Intensity Focused Ultrasound (HIFU YDME AESKULAP) is a highly precise medical procedure that applies high-intensity focused sonic energy to locally heat and destroy disease or damaged Tumor Cancer tissue through ablation. Clinical HIFU YDME AESKULAP procedures are typically performed in conjunction with an imaging procedure to enable treatment planning and targeting before applying a therapeutic or ablative levels of ultrasound energy.
Currently, HIFU YDME AESKULAP has been approved therapeutic procedure to cancer treatment in various countries in Thailand, Australia, Canada, Europe, and the United States. At this time HIFU devices are cleared to be on the market in the US, Canada, EU, Australia, and several countries in Asia.
Aeskulap Clinic (Asia) is the first company to introduce HIFU therapy system in Thailand through the cooperation with Medical School of Srinakharintarawirot University (MEDSWU) to start clinical trials to evaluate the effectiveness of the HIFU YDME AESKULAP devices to ensure absolute safety and less complication for providing to the public. Now, HIFU YDME AESKULAP in operation and service at The Royal Highness Princess Maha Chakri Sirindhorn Hospitals.
In 2010
Tissue Engineering Development by Robot Automate Cell Culturing System (RCPX) with Kawasaki Heavy Industries Limited
RCPX (Robot Automated Cell Culturing Systems).
The Company has been entered to RCPX (Robot Automated Cell Culturing Systems) for regenerative medicine and cell therapy using automatic cell processing system and also invented to increase abilities in culturing cell both in term of quantity and quality. The RCPX is the robotic system in nature, it still needs competent personnel to initiate the cell line and introduce to the robotic system. Indeed, it has high efficiency to produce products in commercial scale.
RCPX (The Advantage from RCPX “Robot Automated Cell Culturing Systems”)
The Substitute of CPC (Cell Processing Center)
The automatic cell processing system will end the need of CPC with high cost of building and maintenance. As it has globe box function, it is used as an isolator. The best formation by combining of automation and manual method is achieved.
Mass production of cells in safety, steadily and stably is achieved. The individual recognition is installed on the equipments such as culture vessels, and the mix-up is prevented.
The Contamination Control by VHP (Vaporized Hydrogen Peroxide) makes sure the prevention of cross contamination between plural donors. As wastes are taken out after decontamination medical staffs are kept safety.
As commonly used culture protocols for adherent cells are automated, it enables the culture of large variety of cells with changing parameters and making software.
As all facilities are computer-controlled, all operation of the system, robot movements and the state of cell including their image data are recorded. Remote monitoring and remote control are possible using network connection.
Wide varieties of protocols for cell culture and tissue engineering are automated, example: Culture of bone marrow mesechymal stem cell, Isolating Keratinocytes Cultured Epidermis Sheet, Transplantation of Autologous Cultured Cartilage “Knee-Joint”), Transplatation of Autologous Cultured Cornea Epithelium.
The advances in the fields of biotechnology and biomaterials offer the physician the exciting possibility of repair or regeneration of tissue lost to injury, disease, or aging. The tissue-engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physic-chemical factors. The promising area of tissue engineering represents a multidisciplinary approach aimed at solving some of the most perplexing biologic problems, namely, the creation of new tissues and organs similar to the original tissues and organs. In addition, strategies using new synthetic polymer formulations can facilitate tissue replacement and represent alternatives to tissue regeneration in certain conditions.
•Cultured Epidermis is the world’s most widely used Tissue-Engineered Medical Product (TEMP). AESKULAP is the first will offer it in Thailand.Cultured Epidermis is skin cover the human body completely. An average adult
Has a total surface are of around 1.6 m2 of skin, which if subcutaneous tissue is included weight around 9 kg. Skin is the largest organ of the human body. If a burn or other trauma results in skin loss over a wide area, this seriously impairs its vital functions of maintaining body temperature and conserving fluid, and infection by bacteria that invade the body from outside also increases the risk of death. Histological, skin comprises three layers; from the outside in, these are epidermis, dermis, and subcutaneous tissue. The keratinocytes that compose the epidermis possess an extremely high ability to proliferate, meaning that skin regenerates very rapidly. When the skin is lost over a wide area, however, regeneration takes too long. A cultured epidermis had been developed that can be grafted onto the injured area, made by isolating keratinocytes from a skin biopsy, culturing them in flaks, and forming them into a skin-like sheet.
•Regenerating your own Cartilage means being able to move yours Joints just as smoothly as you used to. AESKULAP is the first will offer it in Thailand
Cultured cartilage is the thin layer that covers the bones in joints such as knees and elbows, allowing them to move smoothly over each other. In healthy adults this layer is around 2-3 mm thick, but it becomes thinner with advancing age. As cartilage tissue does not naturally recover once damaged. It is extremely difficult to treat with drugs or other therapies. Now, however the latest tissue-engineering technology means cartilage can be regenerated in a culture dish as cultured cartilage.
•Cultured Corneal Epithelium Offers a New Vision for formerly untreatable Eye Disorders. AESKULAP is the first will offer it in Thailand
Cultured cornea epithelium forms the outermost layer of the cornea in the eye. Within the cornea epithelium, Stem cells are found in the region called the limbus on the border between the cornea and the conjunctiva. In cases of severe injury to the cornea, as long as even a small patch of healthy limbus remains, cornea epithelial stem cells can be isolated from this limbus tissue and cultured to produce autologous cultured cornea epithelium. Transplanting this tissue makes it possible for patients to recover their vision unheard of with conventional treatments.
In 2012
The Company entered to an agreement with Japan Tissue Engineering Co., Ltd to penetrate the Tissue Engineering to be Regenerative Medicine for Cultured Epidermis, Transplantation of Autologous Cultured Cartilage (Knee-Joint), Cultured Corneal Epithelium
In 2013, 1st Half
The Company decided to invest into an Advance Innovation Biotechnology by building up the new building for Holistic & Wellness (Preventive and Rehabilitation), Dermatology and the highest quality of cosmetic products Centre at Centre of Bangkok City (Ngamwongwan Road) and UNESCO World Heritage at Khao Yai for 40 rai “Castle Holistic & Wellness (Preventive and Rehabilitation), Dermatology and the highest quality of Cosmetic products in the “Castle Hotel”, Total amount of investment approx. Million U.S Dollars 36.00.
In 2013, 2nd Half
The Company decided to enter into Activated Autologous Lymphocyte Therapy with Toyo Seikan Kaisha, Ltd. And Lymphotec, Inc which these new venture therapy systems will be supported and value added treatment with the existing Cancer Centre treatment by High Intensity Focused Ultrasound (HIFU YDME AESKULAP) at The Royal Highness Princess Maha Chakri Sirindhorn Hospitals.
Recents Business Developments
Thanawin Holdings Co., Ltd. was established in 1993 by Dhanakiccapavaraphan Family with the registered capital of 3.5 Million U.S. Dollars and approximately 88 Million U.S. Dollars in tangible assets.
Thanawin Holding Company is an investment company engaged in various business areas including the areas of biotechnology, import and export of biotechnology transfer, real estate development, energy supply (NGV) service provider, highest technology of medical device (HIFU YDME AESKULAP, RTM, Ozone Therapy Systems, Cycroterm, Multiwave Osilator, Acu Vision, Acu Point, Frequency Generator, etc.), dermatology and the highest quality cosmetic which they are the latest technology of skin care products as well as organic and macrobiotic serving at our quick service restaurant.
Thanawin Holding Company is also involved with the Tumor Cancer Center at The Royal Highness Princess Maha Chakri Sirindhorn, Srinakharinwirot University Hospital tissue engineering at Chulalongkorn Faculty of Medicine, immunology research at Chulalongkorn Faculty of Medicine and Chiang Mai Faculty of Medicine, Srinakarinwirot Faculty of Medicine and a wellness
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