Cigarette smoking is a major public health issue in both the US and worldwide placing an enormous burden on the US economy. Approximately 20% (~60 million) of Americans smoke [1]. In addition, in 2008 in the US, approximately 88 million nonsmokers aged ≥3 years were exposed to second-hand smoke [2]. Previous declines in rates of tobacco use have stalled over the past 5 years [3]. Cigarette smoking (first- and second-hand) and exposure to nicotine are associated with premature death from chronic diseases, economic losses to society, and a substantial public health burden [4]. The Centers for Disease Control (CDC) estimate that, between the years 2000 and 2004, the average annual productivity losses attributable to smoking were approximately $96.8 billion [4]. Tobacco use has remained a particular burden for those below the poverty line [5], thus contributing to some of the health disparities in the US.